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Brannigan Lab

Sustainable Polymer Chemistry

& Degradable Biomaterials

The development of novel application-driven biomaterials has a profound impact on human health care and is essential for the advancement of medicine. Through multidisciplinary collaborations between polymer chemists, biologists, and clinicians, innovative strategies and materials have been created to analyse and treat a range of diseases. Applications of polymeric biomaterials include medical devices, diagnostics, sensors, drug delivery systems and tissue engineering.

Although major advancements have occurred in tailored patient care over the past decade, innovation in advanced polymeric biomaterials offers a unique platform to overcome many challenges still faced in biomedical sciences. We are particularly interested in adhesive materials for wound healing, novel polymers for tissue regeneration/engineering, and advanced drug delivery systems for targeted delivery of active pharmaceutical ingredients.

Relevant publications

  • Biocompatible polypeptide-based interpenetrating network (IPN) hydrogels with enhanced mechanical properties, S. O’Brien; R. P. Brannigan; R. Ibanez; B. Wu; J. O’Dwyer; F. J. O’Brien; S-A. Cryan; A. Heise, 2020, Journal of Materials Chemistry B, 8, 7785-7791.

  • pH-responsive, functionalizable spyrocyclic polycarbonate: a versatile platform for biocompatible nanoparticles, M. C Arno; R. P. Brannigan; G. M. Policastro; M. L. Becker; A. P. Dove, 2018, Biomacromolecules, 8, 3427-3434.

  • Synthesis and evaluation of mucoadhesive acryloyl-quaternized PDMAEMA nanogels for ocular drug delivery, R. P. Brannigan; V. V. Khutoryanskiy, 2017, Colloids and Surfaces B: Biointerfaces, 155, 538-543.

Biomaterials and drug delivery

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